Melek Türker Saçan

Office: 
HKC-313
e-mail: 
msacan@bogazici.edu.tr
web: 
http://web.boun.edu.tr/msacan/ Ecotoxicology and Chemometrics Lab
Phone: 
+90 212 359 4598
Interest Areas: 

Ecotoxicology

Quantitative Structure-Activity Relationships – QSARs

Quantitative Structure-Toxicity Relationships – QSTRs

Pollution monitoring

Algae

Education: 

Ph.D., Institute of Environmental Sciences, Boğaziçi University, TR, 1990

M.S., Institute of Environmental Sciences, Boğaziçi University, TR, 1987

B.S., Department of Chemistry, Boğaziçi University, TR, 1985

Academic Career: 

Professor, Institute of Environmental Sciences, Bogazici University, Istanbul, 2006- Present

Associate Professor, Institute of Environmental Sciences, Bogazici University, Istanbul, 2002-2006

Associate Professor, Faculty of Science Department of Biology, Istanbu University, Istanbul, 2000-2002

Assistant Professor, Faculty of Science Department of Biology, Istanbu University, Istanbul, 1994-2000

Instructor, Faculty of Arts and Sciences Department of Chemistry, Bogazici University, Istanbul, 1990- 1994

Research Assistant, Faculty of Arts and Sciences Department of Chemistry, Bogazici University, Istanbul, 1989-1990

Research Assistant, Institute of Environmental Sciences, Bogazici University, Istanbul, 1985-1989

Recent Projects: 
  1. “A Computational Assessment of Potential Environmental Effects for Nano-sized Molecules of Fullerene Derivatives”, The Scientific and Technological Research Council of Turkey (TUBITAK) and Slovenian Research Institute (ARRS), 2020-2023.
  2. “Toxicity Assessment of Pesticides with no Ecotoxicological Data to Freshwater Algae, (BU, BAP) 2017-2019”
  3. “In silico models for environmentally and biologically relevant endpoints”, The Scientific and Technological Research Council of Turkey (TUBITAK) and Slovenian Research Institute (ARRS), 2015- 2018
  4. “Assessment and in silico modelling of the toxicity of selected emerging pollutants to Chlorella vulgaris”, (BU, BAP), 2014-2016
  5. “Microalgal response to methyl and nitro substituted phenols”, (BU, BAP), 2013
  6. “QSAR modeling of toxicity based on measured aquatic algae toxicity data”, The Scientific and Technological Research Council of Turkey (TUBITAK) and Slovenian Research Institute (ARRS), 2008-2012.
Selected Publications: 
  1. Fjodorova N, Novič M, Venko K, Drgan V, Rasulev B, Saçan MT, Erdem SS, Tugcu G, Toropova AP; Toropov AA (2022). How fullerene derivatives (FDs) act on therapeutically important targets associated with diabetic diseases. Computational and Structural Biotechnology Journal, 2022, 20, 913-924.
  2. Saçan MT., Önlü S., Tugcu G., “Chemometric Modeling of Algal Toxicity” In: Roy, K. (eds) Chemometrics and Cheminformatics in Aquatic Toxicology, Chapter 14, 2021, 274-189, John Wiley & Sons.
  3. Tugcu G., Önlü S., Aydın A., Saçan MT., Read-Across for Regulatory Ecotoxicology. In: Roy, K. (eds) Ecotoxicological QSARs. Methods in Pharmacology and Toxicology, 2020, Chapter 13, 289–304, Humana, New York, NY.
  4. Gökçe S, Saçan MT. “Assessments of Algal Toxicity and PBT Behaviour of Pesticides with No Eco‐toxicological Data: Predictive Ability of QSA/(T)R Models”, Molecular Informatics, 2019, 38, 1800137
  5. Kahraman EN, Saçan MT. “Predicting Cytotoxicity and Enzymatic Activity of Diverse Chemicals Using Goldfish Scale Tissue and Topminnow Hepatoma Cell Line‐based Data”, Molecular Informatics, 2019, 38, 1800127.